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In conclusion, our structural and functional analyses provide a large body of novel information for defining the molecular mechanism underlying the activation of c-MET in response to HGF and NK1 and paves the way for the eventual therapeutic intervention of diseases caused by aberrant activation of c-MET
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This mitochondrial failure results in the immune senescence of those same T cells and a systemic accelerated aging phenotype, marked by motor deficits, cardiovascular dysfunction, and cognitive decline ( Sleep supports mitochondrial restoration through enhanced antioxidant defenses, autophagy, and bioenergetic recovery (Mauri et al., 2022
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