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These estrogen-mimicking chemicals can bind to the estrogen receptors, similarly to the way that estrogen binds.[ref][ref] Phthalates are used in vinyl, plastics, adhesives, artificial fragrances (laundry detergent, air freshener), personal care products, and more.[ref] Related article : Phthalates and detoxification pathways BPA is also found in plastics, and we are exposed through food and drinks being stored in plastic containers or cans with linings containing BPA

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Although targeted therapies have improved outcomes, resistance remains a challenge, particularly in high-risk patients with TP53 mutations or unmutated immunoglobulin heavy-chain variable region (IGHV) genes (U-CLL)