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In a rat liver fibrosis model, the upregulation of HO-1 induced by magnesium isoglycyrrhizinate promoted the accumulation of iron and lipid peroxide, resulting in the ferroptosis of HSCs, while the antifibrotic effect of magnesium isoglycyrrhizinate was eliminated when ferrostatin-1 was used or HO-1 was silenced (Sui et al., 2018)
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Cardio Metabolic products - Oxidative stress is the biggest culprit in modern lifestyle that puts the load of free radicals and organ damage
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