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This binding triggers an inflammatory response, activating nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs), leading to the production of pro-inflammatory cytokines such as TNF- α , IL-1β, and IL-6 (55)
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[DOI] [PubMed] [Google Scholar] 9.Marchesi VT, Furthmayr H, Tomita M
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