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In the face of vitamin B 12 deficiency, conversion of methylmalonyl-CoA to succinyl-CoA cannot take place, which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis
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Tesofensine is one of the most-referenced members and is frequently used as a probe of dopamine-transporter occupancy in mechanistic studies (Appel et al., 2014)
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