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Excessive dryness in the eye can lead to: Corneal abrasions – Scratches on the eye’s surface caused by a foreign object Corneal ulcers – Open sores on the cornea Corneal erosions – Scratches on the eye’s surface due to dry eye and exposure Keratitis – Infection of the cornea Conjunctivitis – Infection of the membrane that covers the whites of the eyes (conjunctiva) Ingrown eyelashes (trichiasis) Madarosis (eyelash loss) It’s important to maintain corneal protection by keeping the eyes hydrated

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Instead, Vederas and coworkers synthesized and fed 13 C-labeled acyl-SNACs as precursors to the dehydrocurvularin and hypothemycin PKSs to compete with natural acyl intermediates, and used 13 C NMR of the resulting products to verify incorporation of the advanced acyl intermediates