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How BPC-157 Triggers New Blood Vessels (VEGF) BPC-157 triggers new blood vessel formation mainly at the receptor end of the VEGF axis: in ischemic rat hind-limb muscle and human endothelial cells it raised VEGFR2 expression, promoted VEGFR2 internalization, and activated VEGFR2-Akt-eNOS signaling, while VEGF-A itself was not increased (PMID 27847966)
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