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The gene trapping of mito-fusion protein Mfn2 or OPA1 in ESCs exhibits the same phenotype—the differentiation of ESCs to cardiomyocytes is blunted [12]
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It was reported that edaravone inhibited ferroptosis by scavenging chain-initiating water-soluble radicals and chain-carrying lipid peroxyl radicals due to its amphiphilicity, in ischemic stroke and amyotrophic lateral sclerosis (Homma et al., 2019
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