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Furthermore, H 2 S levels can be indirectly increased through the activity of cysteinyl t-RNA synthetase (CARS) enzymes, which have been shown to produce cysteine persulfide that can then be metabolized to H 2 S and other sulfur species (Akaike, Ida et al
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The antitumor activity of compounds 41 , 42 , 45 , 46 , and 47 was evaluated against prostate cancer resistant to AR-targeted therapy cell line 22Rv1, which is an aggressive type of cancer with a low survival rate
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