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PRP also promotes skin fibroblast collagen synthesis and expression of MMPs (90), while Alb-PRF has similar effect to other PRF preparations to stimulate gingival fibroblast expression of TGFB1 and COL1A1, albeit with an extended effect up to 7 days (92) compared early (6 h) gene expression changes in gingival fibroblasts treated with PRF membrane lysates and PRF serum (liquid exudate released during membrane preparation) to non-treated cells by bulk RNA sequencing
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doi: 10.1016/j.anl.2006.09.021 [DOI] [PubMed] [Google Scholar] 132.de Azevedo AA, Langguth B, de Oliveira PM, Figueiredo RR
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