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In addition, overexpression of lipoprotein lipase (LPL) in liver or muscle induced peripheral insulin resistance and the accumulation of lipid in respective tissues [87,88], and skeletal muscle-specific LPL deletion enhanced insulin signaling in HFD challenged muscle [89]
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Serine depletion promotes antitumor immunity by activating mitochondrial DNA-mediated cGAS-STING signaling
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