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The risk of PD is increased by exposure to neurotoxins and pesticides and through oxidative damage to neurons by a decrease in the mitochondrial complex I activity and glutathione levels [18, 45-49]
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More recently, a child with short stature (height β3.6 SD at age 9 years) from a consanguineous Serbian family was reported to have a homozygous missense mutation, C53S, of GH1 leading to the absence of the disulfide bridge Cys-53 to Cys-165 in the GH molecule (Besson et al., 2005)
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