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Metformin (Glucophage) belongs to a class of oral diabetes medication called biguanides — biguanides are antihyperglycemic drugs that prevent the production of glucose in the liver, improving the body’s sensitivity to insulin and reducing the amount of sugar absorbed by the intestines
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A Bayesian network meta-analysis of five randomized controlled trials provides moderate-certainty evidence that cagrilintide–semaglutide combination (CagriSema0 results in greater reductions in glycated hemoglobin and body weight compared with semaglutide or cagrilintide alone
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