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A related fragment, AOD-9401, raised lipolysis and reduced lipogenesis in isolated human adipose tissue in vitro (Heffernan et al., Am J Physiol Endocrinol Metab, 2000)
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These compounds reduce 1-MNA levels in mice [23,75,87], and high 1-MNA concentrations have been linked to type 2 diabetes mellitus and obesity in humans [88]
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