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thus, the expression patterns of pro-inflammatory, anti-inflammatory, progenitor, and extracellular matrix molecular markers can allow us to define new therapeutic targets and provide a better understanding of the underlying mechanisms of disc degeneration [35]

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Macromolecules such as proteins, polysaccharides, nucleic acids differ only in their physico-chemical properties within the individual groups and their isolation on the basis of these differences is therefore difficult and time consuming