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Apical acidity decreases inhibitory effect of omeprazole on Mg(2+) absorption and claudin-7 and -12 expression in Caco-2 monolayers
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These TJs play a crucial role in preserving epithelial polarity and ensuring the proper functioning of the paracellular barrier as a physical barrier against luminal content including microorganisms, antigens, and xenobiotics [1,[5], [6], [7]]
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