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In contrast, results from population-based cohorts suggest that decreased numbers of CD4 + Tregs in the peripheral circulation are associated with poor prognosis in IS ( + T cells in the IS process, with another subpopulation of CD4 + T cells, Th17 cells, also gaining attention
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ceruloplasmin is still secreted, but in a form that lacks copper (termed apoceruloplasmin) and rapidly degraded in the bloodstream.[16] When the amount of copper in the liver overwhelms the proteins that normally bind it, it causes oxidative damage through a process known as Fenton chemistry
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