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A threshold period of 4.5 months appears to emerge from the results of the analyzed studies, indicating that, beyond this period and in neuromas larger than 5-6 mm, orthotics and/or shoes modifications do not seem to give convincing results, proving to be more a palliation for the clinical condition to allow an acceptable life with pain rather than a real treatment.” Failure after surgery – The failure rate following surgical excision has been reported as up to 30% A May 2020 study ( 8 ) examined the failure rate of Morton’s Neuroma surgery: “The failure rate following surgical excision has been reported as up to 30%

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Nature 450 : 1230–1234